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Joshua M Hare Selected Research

Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)

1/2023Efficacy of a growth hormone-releasing hormone agonist in a murine model of cardiometabolic heart failure with preserved ejection fraction.
1/2023Synthetic growth hormone-releasing hormone agonist ameliorates the myocardial pathophysiology characteristic of heart failure with preserved ejection fraction.
1/2021Growth hormone-releasing hormone agonists ameliorate chronic kidney disease-induced heart failure with preserved ejection fraction.
11/2017Growth hormone-releasing hormone attenuates cardiac hypertrophy and improves heart function in pressure overload-induced heart failure.
3/2015Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine with subacute ischemic cardiomyopathy.
1/2015New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor.
1/2012Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI).
2/2010Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction.

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Joshua M Hare Research Topics

Disease

67Heart Failure
01/2023 - 02/2002
42Myocardial Infarction
02/2024 - 08/2005
25Cardiomyopathies (Cardiomyopathy)
01/2023 - 05/2004
17Heart Diseases (Heart Disease)
11/2020 - 10/2001
16Cardiovascular Diseases (Cardiovascular Disease)
01/2021 - 03/2004
11Inflammation (Inflammations)
01/2023 - 12/2010
11Cicatrix (Scar)
01/2021 - 08/2005
10Infarction (Infarctions)
03/2017 - 01/2006
9Cardiomegaly (Heart Hypertrophy)
01/2023 - 06/2003
8Fibrosis (Cirrhosis)
01/2023 - 01/2010
8Hypertrophy
01/2023 - 08/2003
7Myocarditis (Carditis)
11/2022 - 10/2001
6COVID-19
11/2022 - 01/2020
6Hypoxia (Hypoxemia)
11/2022 - 04/2009
5Pulmonary Hypertension
11/2022 - 04/2002
5Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2021 - 02/2006
5Reperfusion Injury
11/2019 - 03/2004
5Obesity
05/2007 - 08/2003
4Hypoplastic Left Heart Syndrome
03/2023 - 10/2017
4Congenital Heart Defects (Congenital Heart Defect)
01/2023 - 09/2016
4Neoplasms (Cancer)
10/2022 - 10/2018
4Left Ventricular Dysfunction
01/2019 - 11/2005
4Frailty
01/2018 - 03/2016
4Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
12/2015 - 06/2003
4Ventricular Remodeling
05/2013 - 04/2009
3Hyperlipidemias (Hyperlipidemia)
03/2024 - 01/2022
3Stroke (Strokes)
02/2024 - 04/2017
3Atherosclerosis
04/2023 - 01/2004
3Hypertension (High Blood Pressure)
06/2022 - 03/2004
3Body Weight (Weight, Body)
01/2022 - 08/2003
3Proteinuria
01/2022 - 10/2018
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2018 - 10/2001
3Vascular Remodeling
04/2016 - 06/2009
2Disease Progression
01/2023 - 10/2007
2Vascular Diseases (Vascular Disease)
11/2022 - 08/2013
2Infections
11/2022 - 01/2020
2Prostatic Neoplasms (Prostate Cancer)
10/2022 - 10/2018
2Chronic Renal Insufficiency
01/2022 - 01/2021
2Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2022 - 01/2020
2Ischemic Stroke
01/2021 - 08/2012
2Erectile Dysfunction
01/2020 - 08/2012
2Cardiac Arrhythmias (Arrythmia)
11/2019 - 11/2009
2Myocardial Ischemia (Ischemic Heart Diseases)
11/2019 - 04/2008
2Segmental glomerulosclerosis
11/2019 - 10/2018
2Lipoid Nephrosis (Glomerulonephritis, Minimal Change)
11/2019 - 10/2018
2Parkinson Disease (Parkinson's Disease)
10/2019 - 02/2014
2Hypogonadism (Hypergonadotropic Hypogonadism)
01/2019 - 01/2018
2Peripheral Arterial Disease
04/2017 - 08/2012

Drug/Important Bio-Agent (IBA)

14Biomarkers (Surrogate Marker)IBA
11/2020 - 11/2004
12Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2021 - 10/2001
11Xanthine OxidaseIBA
05/2015 - 04/2003
8Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
01/2023 - 02/2010
8Proteins (Proteins, Gene)FDA Link
01/2022 - 03/2004
8Uric Acid (Urate)IBA
10/2019 - 04/2003
6somatotropin releasing hormone receptorIBA
01/2023 - 01/2012
6LeptinIBA
06/2011 - 08/2003
5CytokinesIBA
10/2022 - 04/2010
5glutathione-independent formaldehyde dehydrogenase (formaldehyde dehydrogenase)IBA
01/2022 - 04/2009
5Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022 - 10/2001
4omega-Chloroacetophenone (Mace)IBA
02/2024 - 01/2018
3Brain Natriuretic Peptide (Natrecor)FDA Link
01/2023 - 03/2007
3Testosterone (Sustanon)FDA Link
01/2022 - 01/2019
3erucylphosphocholineIBA
07/2021 - 12/2010
3Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2018 - 09/2006
3Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
01/2017 - 12/2007
3Stem Cell FactorIBA
04/2016 - 09/2006
3CalciumIBA
09/2014 - 12/2007
3Phosphates (Orthophosphate)IBA
01/2013 - 11/2009
3Xanthine DehydrogenaseIBA
01/2009 - 03/2004
3Adrenergic Agents (Adrenergic Drugs)IBA
03/2007 - 06/2005
3Allopurinol (Remid)FDA LinkGeneric
03/2007 - 02/2002
2LDL Receptors (LDL Receptor)IBA
03/2024 - 01/2022
2Troponin T (Troponin T1)IBA
03/2024 - 01/2022
2MicroRNAs (MicroRNA)IBA
04/2023 - 01/2012
2MR 356IBA
01/2023 - 02/2014
2COVID-19 VaccinesIBA
11/2022 - 11/2022
2S-NitrosothiolsIBA
10/2022 - 04/2009
2S-NitrosoglutathioneIBA
10/2022 - 10/2018
2cytidylyl-(3'-5')-cytidine (CpC)IBA
10/2022 - 01/2017
2Oxygen (Dioxygen)IBA
12/2021 - 12/2016
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
07/2021 - 06/2003
2AnthracyclinesIBA
11/2020 - 01/2018
2Neutralizing AntibodiesIBA
01/2020 - 04/2016
2Puromycin AminonucleosideIBA
11/2019 - 10/2018
2AntioxidantsIBA
10/2019 - 02/2002
2InosineFDA Link
10/2019 - 02/2014
2Reactive Nitrogen SpeciesIBA
01/2018 - 10/2009
2N-Me-Tyr1,D-Ala2,Asn8,Arg29-NHCH3-JI-38IBA
11/2017 - 02/2014
2N 30IBA
10/2017 - 01/2015
2Phosphotransferases (Kinase)IBA
12/2016 - 01/2013
2Conditioned Culture MediaIBA
12/2016 - 10/2010

Therapy/Procedure

92Therapeutics
07/2023 - 04/2002
21Cell- and Tissue-Based Therapy (Cell Therapy)
06/2022 - 03/2008
12Injections
01/2021 - 08/2009
4Heart Transplantation (Grafting, Heart)
10/2017 - 08/2005
3Intravenous Injections
03/2024 - 03/2017
3Intraperitoneal Injections
03/2024 - 06/2009
3Catheters
08/2009 - 08/2005
2Castration
10/2022 - 10/2018
2Patient Readmission
11/2017 - 10/2007